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The best guest houses in Santa Cruz Region

Check out our pick of great guest houses in Santa Cruz Region

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Review score

Superb: 9+ Very good: 8+ Good: 7+ Pleasant: 6+
Our top picks Lowest price first Star rating and price Top reviewed

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Hostel Serena

Samaipata

Hostel Serena in Samaipata offers free WiFi and private parking on site, the hostel is open 24 hours per day.

We can arrange your private taxi from the airport straight to the hostel if you want, for a cheap price if you want.

Hostel Serena has been welcoming Booking.com guests since Dec 27, 2016 -- Friendly owner, beautiful place.

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9.3
Superb
424 reviews
Price from
US$17.60
per night

Posada Guasu

Samaipata

Located in Samaipata, 9.3 km from Samaipata Fort, Posada Guasu provides accommodation with a garden, private parking and a shared lounge. The accommodation features room service, a 24-hour front desk and organising tours for guests.

The inn offers certain rooms with garden views, and the rooms come with a patio. At Posada Guasu each room comes with bed linen and towels. A beautiful bed and breakfast in Samaipata in a heritage building. The owner Lina is lovely - in addition to always looking like a movie star she is so helpful and accommodating. She prepared an excellent breakfast every day as well!

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9.3
Superb
256 reviews
Price from
US$18.18
per night

Casa del Telegrafista

La Higuera

Casa del Telegrafista features a garden, terrace, a restaurant and bar in La Higuera. Featuring family rooms, this property also provides guests with a barbecue. The accommodation provides room service, a tour desk and currency exchange for guests.

At the inn, each room includes a patio with a mountain view. The place is beautiful and a paradise. Our room was comfortable with attached bathroom, there is a patio outside where you can rest and look at nature that is all around you, the only sound is from the birds and the wind. You can also eat in the little bar/caffe, it's really well made and full of Che's pictures. We had breakfast every morning, was so big that we didn't eat for half day. Oda is kind and helpful and she loves her place. There is also a communal kitchen that you can use. I loved the village as well, so quiet and with lots of history.

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9.3
Superb
23 reviews
Price from
US$16.50
per night

Hostal Backpackers Travelero

Santa Cruz de la Sierra

Situated just less than 1 km from Arenal Park, Hostal Backpackers Travelero offers accommodation in Santa Cruz de la Sierra with access to an outdoor swimming pool, a garden, as well as a 24-hour front desk. The property has pool views and is 1.2 km from 24th of September Metropolitan Plaza and 1.4 km from Sacred Art Museum. The guest house features rooms with air conditioning, free private parking and free WiFi. Great location near restaurants close grocery stores, coffee shops. Nice clean room. Helpful staff.

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8.9
Fabulous
477 reviews
Price from
US$12
per night

Andoriña Hostal - Bed & Breakfast

Samaipata

Located in Samaipata, 9.1 km from Samaipata Fort, Andoriña Hostal - Bed & Breakfast provides accommodation with a garden, free WiFi, a shared kitchen, and luggage storage space. The property has city and inner courtyard views. The guest house features family rooms. The best breakfast we had and staff was very helpful, especially with arranging buses.

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8.8
Fabulous
222 reviews
Price from
US$12.40
per night

Fonda Amboró

Samaipata

With a private bathroom equipped with a shower and free toiletries, units at the guest house also offer free WiFi, while selected rooms come with a terrace.

Buffet and continental breakfast options with pancakes, fruits and juice are available daily at the guest house. Beds were very good, spacious bedrooms, good shower and bathroom, fully equipped kitchen, delicious breakfast with homemade bread and jam, very nice attention of Adrian.

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8.6
Fabulous
47 reviews
Price from
US$37.40
per night

Casa Rural Doña Blanca

Samaipata

Situated in Samaipata and only 10 km from Samaipata Fort, Casa Rural Doña Blanca features accommodation with mountain views, free WiFi and free private parking. The property features garden views. The guest house has family rooms. The place is big and has a very nice view. It also has parking space and it is just a few blocks from the city center. We had a nice stay overall.

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8.4
Very good
8 reviews
Price from
US$31.46
per night

Casa Sayana

Samaipata

Casa Sayana provides a garden, as well as accommodation with a kitchen in Samaipata, 10 km from Samaipata Fort. Featuring mountain and garden views, this guest house also provides guests with free WiFi. The guest house has private entrance. This is a lovely hostel where you can relax and feel cosy! Maria is a wonderful host. I extended several days and loved it. All your needs are met there…

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7.8
Good
135 reviews
Price from
US$8.80
per night

La Casona

Santa Cruz de la Sierra

At the guest house, units are fitted with a wardrobe, a flat-screen TV, a private bathroom, bed linen and towels.

Popular points of interest near the guest house include Arenal Park, Sacred Art Museum and Metropolitan Cathedral. The nearest airport is Viru Viru International, 14 km from La Casona, and the property offers a paid airport shuttle service.

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10
Exceptional
1 reviews
Price from
US$30
per night

Hostal Plaza de la Concordia

Santa Cruz de la Sierra

Hostal Plaza de la Concordia is set in Santa Cruz de la Sierra, 400 metres from Metropolitan Cathedral, 400 metres from 24th of September Metropolitan Plaza, and 1.1 km from Arenal Park. The air-conditioned accommodation is 200 metres from Sacred Art Museum. The guest house features family rooms.

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7
Good
3 reviews

Most booked guest houses in Santa Cruz Region this month

FAQs about guest houses in Santa Cruz Region

  • Most guest houses on Booking.com offer free cancellation.

  • Couples travelling in Santa Cruz Region loved staying at Hostel Serena, Andoriña Hostal - Bed & Breakfast and Fonda Amboró.

  • The average price per night for a guest house in Santa Cruz Region for this weekend is US$53, based on current Booking.com prices.

  • Many families visiting Santa Cruz Region loved staying at Casa Rural Doña Blanca, Hostel Serena and Andoriña Hostal - Bed & Breakfast.

  • Hostel Serena, Hostal Backpackers Travelero and Andoriña Hostal - Bed & Breakfast are some popular guest houses in Santa Cruz Region.

  • There are 17 guest houses in Santa Cruz Region you can book on Booking.com.

  • Hostal Backpackers Travelero, Hostel Serena and Andoriña Hostal - Bed & Breakfast have received great reviews from guests in Santa Cruz Region regarding the views from these guest houses

  • We make it quick and easy to book a guest house in Santa Cruz Region. Here’s what we offer:

    • Free cancellation on most stays
    • We Price Match
    • 24/7 customer support in 40+ languages

Guest Houses that guests love in Santa Cruz Region